Academic Experts
Academic Experts
Prof. Reema Gabrani
Professor
reema.gabrani@jiit.ac.in
Biography

Professor Reema Gabrani is a Senior Faculty Member in the Department of Biotechnology at Jaypee Institute of Information Technology (JIIT), Noida, with over two decades of experience in academia, research, and institutional leadership. She earned her Ph.D. in Biotechnology from the National Institute of Immunology, New Delhi, following a Master’s in Biotechnology and a B.Sc. (Hons.) in Human Biology from All India Institute of Medical Sciences (AIIMS), New Delhi. She further enhanced her expertise through postdoctoral research in Molecular Virology at the University of Minnesota, USA, gaining international experience.

Since joining JIIT in 2004, Professor Gabrani has made significant contributions to cancer therapeutics, molecular virology, and antimicrobial resistance. Her academic portfolio includes over 100 publications in reputed international journals, several book chapters, and two patents, with successful technology transfers to industry. She has organized the Faculty Development Programme, National and International conferences, fostering collaborative and interdisciplinary research initiatives.

Her vision emphasizes integrating high-impact research with translational outcomes, bridging laboratory innovation with clinical and industrial applications. As an educator and mentor, she inspires students and researchers to pursue innovation, build partnerships, and develop solutions to pressing challenges in health and biotechnology.

Research Highlights

Professor Gabrani’s research focuses on cancer therapeutics, molecular virology, and antimicrobial resistance with a strong translational orientation aimed at solving critical healthcare challenges. A major thrust of her work involves the design of combinatorial therapies for cancer, particularly glioblastoma multiforme, one of the most aggressive brain tumors. She has developed and patented a combination therapy involving temozolomide and D-limonene, which has demonstrated improved therapeutic efficacy and holds promise for better clinical outcomes.

In addition to cancer therapeutics, her research investigates plant-derived bioactive compounds for their antimicrobial and anticancer properties. Employing computational biology and bioinformatics, she systematically identifies and characterizes these compounds, enabling the discovery of novel therapeutic agents. Her work also extends to antimicrobial peptides and the identification of novel molecular targets for infectious diseases, contributing to efforts against antimicrobial resistance.

Professor Gabrani has published over 100 peer-reviewed research articles and contributed to several book chapters. She holds two patents, and a successful Technology Transfer to the Industry, reflecting the real-world impact of her work. Her collaborations with national partners bring a multidisciplinary approach to her projects, enhancing both scope and applicability.

Through her research, Professor Gabrani continues to advance scientific understanding, foster innovation, and contribute to healthcare solutions with tangible societal benefits.

Areas Of Interest
  • Cancer Biology
  • Phytotherapeutics
  • Medical Biotechnology
  • Molecular Virology
  • Drug Resistance
Publications
  • M. Gautam, and R. Gabrani, “Synergism of d-limonene and temozolomide on migratory and apoptotic behaviors of human Glioblastoma cell lines”, Bioimpacts, Vol. 14(5), pp. 27681, January 2024 (IF: 4.0, SCOPUS, SCI)
  • U. Naithani, P. Jain, A. Sachan, P. Khare, R. Gabrani, “MicroRNA as a potential biomarker for systemic lupus erythematosus: pathogenesis and targeted therapy”, Clinical and Experimental Medicine, Vol:23(8), pp. 4065-4077, Dec, 2023. doi: 10.1007/s10238-023-01234-7 (IF: 4.6, SCOPUS, SCI)
  • M. Gautam, R. Gabrani. “Combinatorial Effect of Temozolomide and Naringenin in Human Glioblastoma Multiforme Cell Lines”. Nutrition and Cancer Vol. 74(3), pp. 1071-1078, 2022 doi: 10.1080/01635581.2021.1952438. Epub 2021 Aug 25. (IF: 2.5, SCOPUS, SCI)
  • R. Ghildiyal and R. Gabrani, “Computational analysis of human host binding partners of chikungunya and dengue viruses during coinfection,” Pathogens and Disease, vol. 79, no. 8, Nov. 2021, Art. no. ftab046, doi: 10.1093/femspd/ftab046. (IF: 3.3, SCOPUS, SCI)
  • R. Ghildiyal, R. Gabrani, “Antiviral therapeutics for chikungunya virus” Expert Opinion on Therapeutic Patents, Vol. 30, pp. 467-480, Jun 2020 DOI: 10.1080/13543776.2020.1751817 (IF: 5.0, SCOPUS, SCI)