My research group is exploring the efficacy of phyto-extracts as potential anti-aging and hypoxia-mimetic agents, employing in vitro cellular models and in vivo animal studies to elucidate their mechanistic and translational potential.

Oxygen is a participant in the maximum number of biochemical reactions. Its biological levels are tightly regulated – hypoxia and hyperoxia both have pathological consequences. During my doctoral studies, I worked with rodent models of hypobaric hypoxia (hypoxia experienced at high altitudes due to fall in atmospheric pressure) and investigated several interventions facilitating hypoxia adaptive signaling. Expanding on my expertise in hypoxia biology, I intend to investigate oxygen homeostasis in mammalian systems and its influence on the ageing process. I am also keen on developing suitable biological models to simulate ageing and investigate herbals/phyto-molecules for regulation of oxygen homeostasis.

The globally expanding base of elderly population is also susceptible to infectious diseases due to prevalent inflammaging and other co-morbidities. I am thus also keen on investigating novel and safer antimicrobials.