Academic Experts
Academic Experts
Dr. Manisha Singh
Assistant Professor (Grade - II)
manisha.singh@jiit.ac.in
Biography

Dr. Manisha Singh is an Assistant Professor in the Department of Biotechnology at Jaypee Institute of Information Technology (JIIT), Noida, where she has been serving since 2008. Her research focuses on molecular and genetic mechanisms in CNS disorders, neurosciences, and nanomedicine, with a strong emphasis on translational drug delivery systems for neurodegenerative and respiratory diseases. She earned her Ph.D. in Biotechnology from JIIT and began her career with a fellowship in neurological rehabilitation at Apollo Hospital, New Delhi, followed by teaching roles in neurosciences. Dr. Singh has published over 60 research papers in reputed journals, authored books, contributed more than 30 book chapters, and presented at numerous international forums. She has also been recognized with the Australian Government’s Global Talent Initiative Visa. Internationally, she has worked as a Research Scientist at Flinders University, Australia, contributing to dementia and Alzheimer’s disease research, and later as a Research Fellow at the University of Technology Sydney. She has also collaborated with industry (DE AURORA Pty Ltd Co, Dean Victoria, Australia), securing competitive grants and advancing product development in strategic drug delivery. Currently, she is associated as an Honorary Research Fellow with the Woolcock Institute of Medical Research, Macquarie University, Sydney. Recipient of multiple awards, including Young Research Scientist in Nanotechnology and Excellence in Neurosciences and Nanotechnology, Dr. Singh has also organized international conferences, served on scientific committees, and supervised numerous undergraduate, postgraduate, and PhD students. Dr Singh's multifaceted career, spanning academia, research, and clinical practice, reflects her dedication to the fields of biotechnology, pharmaceutical engineering, and neurosciences. Her contributions continue to impact these fields significantly, both in India and internationally
 

Educational Qualifications

Ph.D. (Field not explicitly mentioned in the text; likely related to Biotechnology/Neurosciences), with advanced fellowships in Neurological Rehabilitation (Apollo Hospital, New Delhi) and extensive postgraduate/clinical training in Biotechnology and Neurosciences.

Research Highlights

Dr. Manisha Singh’s research is centred on the interface of neurosciences, nanomedicine, and translational drug delivery systems with a strong focus on neurodegenerative diseases (NDDs), particularly Alzheimer’s disease. Her work integrates molecular and genetic correlates of CNS disorders with the design of phytoceuticals and nano formulation-based interventions, aiming at early-stage therapeutic strategies. A major thrust of her research has been the design and evaluation of intranasal and nanoparticle-based delivery platforms, enabling targeted and non-invasive approaches for Alzheimer’s disease and related disorders. She has extensively explored phytoceuticals-based nano formulations, leveraging natural compounds to develop safer and more effective therapeutic interventions for early-stage neurodegeneration. Complementing this, her studies on oxidative stress modulation, mitochondrial dysfunction, and neuroinflammation provide key mechanistic insights into disease pathways, bridging fundamental neuroscience with applied therapeutics. Beyond neurodegeneration, Dr. Singh has contributed significantly to respiratory nanomedicine, designing nano formulation strategies for chronic lung diseases and cancer. Her research integrates molecular biology, pharmacology, and computational analysis, positioning her at the forefront of translational drug delivery research. She has also actively engaged in industry-academia collaborations, successfully securing competitive industrial grants for the development of next-generation drug products. These efforts highlight her commitment to translating laboratory findings into clinically relevant solutions with global healthcare impact. Currently, her lab continues to expand the scope of phytoceuticals and nanotechnology-enabled interventions, with the aim of delivering cost-effective, patient-friendly therapies for complex neurological and respiratory conditions. Her work not only advances scientific understanding but also contributes to the development of practical innovations in healthcare.

Areas Of Interest
  • Nanomedicine
  • Neurodegeneration
  • Phytoceuticals drug delivery
  • Brain–Lung Crosstalk
  • Computational Pharmaceutics
Projects
  • Project Title: Assessing the therapeutic potential of Agarwood nano-formulation in neurological conditions 
    Granting Agency: DE AURORA Pty Ltd, Australia (2024 – 2026) and Graduate School of Health, Faculty of Health, Australian Research Consortium in Complementary and Integrative Medicine (ARCCIM) University of Technology Sydney, Sydney, Australia 
    Position as PI. And Co PI Details: PI
    Status: Ongoing
  • Project Title: Preclinical study in Alzheimer’s disease mouse model: Intranasal delivery of curcuminoid for amyloid and cognitive modulation 
    Granting Agency: SMarT Minds WA Pty Ltd., Western Australia and Flinders Health and Medical Research Institute, College of Medicine & Public Health, Flinders’ University, Adelaide, South Australia, Australia (2022-2024) Position as PI. And Co PI Details: Co – PI
    Status: Completed
  • Project Title: Nanoparticle-based Drug delivery system of some antiepileptic drugs for brain drug delivery through nasal route 
    Granting Agency: Department of Biotechnology (DBT), Government of India (2011-2014) 
    Position as PI. And Co PI Details: Co – PI
    Project Cost: 25 Lakhs
    Status: Completed